Archives for March 2025

NanoRoadshow Biotech Exploration – STI 100 Scientists: 100 Schools: 100 Days MOSTI

March 12, 2025 By Editor

On March 4, 2025, INEE, in collaboration with Bioeconomy Corporation (BioCorp), an agency under the Ministry of Science, Technology, and Innovation (MOSTI), organized the NanoRoadshow – Series 5 ‘Biotech Exploration’ program at Dewan Seri Utara, Sekolah Menengah Kebangsaan Padang Besar Utara, Perlis.

This school was selected by MOSTI as part of the STI 100 Scientists 100 Schools 100 Days program for Cycle 1.5. The event was also held in conjunction with the 2025 UniMAP Research and Innovation Excellence Month. Fully sponsored by MOSTI, the program involved more than 50 students from Form 4 and Form 5.

Congratulations to Ts. Dr. Nor Azizah Parmin as the program director. Special thanks to the school, especially the Principal and the entire school management. Deepest appreciation to MOSTI and Bioeconomy Corporation for their sponsorship. May programs like this continue to benefit all students. Thank you!

Visit to the Faculty of Science and Trace Analysis and Biosensor COE, Prince of Songkla University

March 6, 2025 By Editor

A visit was conducted by INEE to the Faculty of Science and the Trace Analysis and Biosensor COE (TAB-COE) at Prince of Songkla University (PSU) on February 24. The Faculty of Science was represented by the Deputy Dean (Academic & International), Assoc. Prof. Dr. Pimonsri Mittraparp-Arthorn, while TAB-COE was represented by its Director, Assoc. Prof. Dr. Chongdee Buranachai.

The meeting, which was also attended by researchers from the Faculty of Science, discussed the Dual-Degree program for postgraduate programs between INEE and the Faculty of Science, PSU. The potential for research collaboration was also explored in depth. Hopefully, this collaboration will continue to thrive.

Fabrication and simulation of silicon nanogaps pH sensor as preliminary study for Retinol Binding Protein 4 (RBP4) detection

March 1, 2025 By Editor

Abstract – In this research, a silicon nanogap biosensor has the potential to play a significant role in the field of biosensors for detecting Retinol Binding Protein 4 (RBP4) molecules due to its unique nanostructure morphology, biocompatibility features, and electrical capabilities. Additionally, as preliminary research for RBP4, a silicon nanogap biosensor with unique molecular gate control for pH measurement was developed. Firstly, using conventional lithography followed by the Reactive-ion etching (RIE) technique, a nanofabrication approach was utilized to produce silicon nanogaps from silicon-on-insulator (SOI) wafers. The critical aspects contributing to the process and size reduction procedures were highlighted to achieve nanometer-scale size. The resulting silicon nanogaps, ranging from 100 nm to 200 nm, were fabricated precisely on the device. Secondly, pH level detection was performed using several types of standard aqueous pH buffer solutions (pH 6, pH 7, pH 12) to test the electrical response of the device. The sensitivity of the silicon nanogap pH sensor was 7.66 pS/pH (R² = 0.97), indicating that the device has a wide range of pH detecting capacity. This also includes the silicon nanogap biosensor validated by simulation, with the sensitivity obtained being 3.24 μA/e.cm² (R² = 0.98). The simulation of the sensitivity is based on the interface charge (Qf) that represents the concentration of RBP4. The results reveal that the silicon nanogap biosensor has excellent characteristics for detecting pH levels and RBP4 with outstanding sensitivity performance. In conclusion, this silicon nanogap biosensor can be used as a new electrical RBP4 biosensor for biomedical diagnostic applications in the future.

Corresponding Author: Assoc. Prof. Dr. Mohammad Nuzaihan Md Nor
Corresponding Author’s Email: m.nuzaihan@unimap.edu.my

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Link to Publication: https://doi.org/10.58915/ijneam.v17iJune.830