Editor, Author at Institute of Nano Electronic Engineering

Multidimensional (0D-3D) nanostructures for lung cancer biomarker analysis: Comprehensive assessment on current diagnostics

July 8, 2019 By Editor

Abstract – The pragmatic outcome of a lung cancer diagnosis is closely interrelated in reducing the number of fatal death caused by the world’s top cancerous disease. Regardless of the advancement made in understanding lung tumor, and its multimodal treatment, in general the percentage of survival remain low. Late diagnosis of a cancerous cell in patients is the major hurdle for the above circumstances. In the new era of a lung cancer diagnosis with low cost, portable and non-invasive clinical sampling, nanotechnology is at its inflection point where current researches focus on the implementation of biosensor conjugated nanomaterials for the generation of the ideal sensing. The present review encloses the superiority of nanomaterials from zero to three-dimensional nanostructures in its discrete and nanocomposites nanotopography on sensing lung cancer biomarkers. Recent researches conducted on definitive nanomaterials and nanocomposites at multiple dimension with distinctive physiochemical property were focused to subside the cases associated with lung cancer through the development of novel biosensors. The hurdles encountered in the recent research and future preference with prognostic clinical lung cancer diagnosis using multidimensional nanomaterials and its composites are presented.

Corresponding Author: Assoc. Prof. Dr. Subash C B Gopinath
Corresponding Author’s Email: subash@unimap.edu.my

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UniMAP researchers invent Nano Lab-On-Chip to detect early stage cervical cancer

July 5, 2019 By Editor

A group of researchers from Universiti Malaysia Perlis (UniMAP) has successfully invented a device to detect early stage cervical cancer. Nano Lab-On-Chip is an electrochemical device with Interdigitated Electrodes (IDE) which are highly sensitive and are able to detect changes in tissues, blood and saliva.

Principal researcher Dr. Nor Azizah Parmin from the Institute of Nano Electronic Engineering (INEE), UniMAP, explains that a sensor chip has been developed to combine voltammetric determination which will be able to quickly detect the cancer-causing Human Papillomavirus (HPV). Early detection is vital as the HPV can be treated, hence increasing the patient’s survival rate. It can also help in controlling the spread of the virus as early detection is crucial in ensuring its mortality. The device will be particularly useful in low and middle income countries that lack advanced technology and those whose patients face issues with access to relevant facilities due to logistical and geographical challenges.

According to Dr Azizah, the presence of the virus can be detected within a few minutes of taking the test. Apart from its use for cancer detection, Nano Lab-On-Chip can also be used for the purpose of environmental control during clinical tests, to check for antibiotic residue in water, to detect formaldehyde gas in wood and for related uses in the furniture industry. The device is cheaper than costs associated with conventional methods, has low fluid volume consumption and fast response time, is reusable and can directly measure real time molecular binding interaction.

Moving forward, the team is currently seeking industry partners or donors to work on enhancing the effectiveness of the sensor. Several agencies are being considered for partnership, including the Ministry of Health and Cancer Detection Centers.

Source: QS WOWNEWS

Under Pressure. Or, 101 Uses For Diamond (Outside of Bling)

July 4, 2019 By Editor

Assalamualaikum and Salam Sejahtera,

Dear Prof/Assoc. Prof./Dr./Mr./Mrs/Ms.,

INVITATION TO PARTICIPATE IN A RESEARCH TALK ON “UNDER PRESSURE. OR, 101 USES FOR DIAMOND (OUTSIDE OF BLING)”

The above matter is referred.

2. Please be informed that Institute of Nano Electronic Engineering (INEE) is going to organize a talk on “UNDER PRESSURE. OR, 101 USES FOR DIAMOND (OUTSIDE OF BLING)”. The details are as follows:

Speaker : Dr. Joe Welch (University College London (UCL))
Date : 26 July 2019 (Friday)
Time : 10.00 a.m. – 12.00 p.m.
Venue : Bilik Seminar Siantan, School of Manufacturing Engineering

3. Kindly find the attached poster for your perusal and disseminate this information to your colleagues, students and other interested parties.

Don’t Miss Out, Come and Join Us!!

Regards,
Committee,
A RESEARCH TALK ON “UNDER PRESSURE. OR, 101 USES FOR DIAMOND (OUTSIDE OF BLING)”

Download Poster: PDF

Current and future envision on developing biosensors aided by 2D molybdenum disulfide (MoS 2 ) productions

July 2, 2019 By Editor

Abstract – Two-dimensional (2D) layered nanomaterials have triggered an intensive interest due to the fascinating physiochemical properties with the exceptional physical, optical and electrical characteristics that transpired from the quantum size effect of their ultra-thin structure. Among the family of 2D nanomaterials, molybdenum disulfide (MoS 2 ) features distinct characteristics related to the existence of direct energy bandgap, which significantly lowers the leakage current and surpasses other 2D materials. In this overview, we expatiate the novel strategies to synthesize MoS 2 that cover techniques such as liquid exfoliation, chemical vapour deposition, mechanical exfoliation, hydrothermal reaction, and Van Der Waal epitaxial growth on the substrate. We extend the discussion on the recent progress in biosensing applications of the produced MoS 2 , highlighting the important surface-to-volume of ultrathin MoS 2 structure, which enhances the overall performance of the devices. Further, envisioned the missing piece with the current MoS 2 -based biosensors towards developing the future strategies.

Corresponding Author: Mohd Khairuddin Md Arshad
Corresponding Author’s Email: mohd.khairuddin@unimap.edu.my

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Visit and Knowledge Sharing from Institute of Advanced Industrial Science and Technology (AIST)

June 24, 2019 By Editor

On 21st June 2019, Institute of Nano Electronic Engineering (INEE) welcomed a delegation from Institute of Advanced Industrial Science and Technology (AIST), Japan, Dr. Makoto Fujimaki. The objectives of this research visit was to identify collaborative opportunities in the field of research in nanotechnology engineering between Japan and Malaysia.

Besides, Dr. Makoto Fujimaki also kindly sharing his valuable knowledge and expertise about Sensors for Detection of Low Concentration of Biological Substances in his research talk during that day.