Institute of Nano Electronic Engineering

Universiti Malaysia Perlis

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Archives for July 2018

The ZnO-FET Biosensor for Cardiac Troponin I

July 23, 2018 By Editor

Abstract – This paper investigates the influence of substrate-gate coupling on the ZnO-FET biosensor’s sensitivity for detection of cardiac troponin I (cTnI), a ‘gold standard’ biomarker for acute myocardial infarction (AMI). The FET-based device with introduction of substrate-gate coupling on p-type silicon-on-insulator (SOI) substrate is fabricated using conventional lithography processes. An n-type zinc oxide (ZnO) thin film deposited via electron-beam evaporator is used as transducer for bridging the source and drain regions. Surface modifications via functionalization with 3-aminopropyltriethoxysilane (APTES) and glutaraldehyde (GA) as chemical linkers, followed by immobilization of cTnI monoclonal antibody (MAb-cTnI) as bio-receptor on the ZnO thin film allow different concentration of cTnI detection with high selectivity. The device’s sensitivity increases up to 9 %•(g/ml)-1 with the increase of the substrate-gate voltage (VSG) up to -10 V at very low limit of detection (LOD) down to 1.6 fg/ml.

Corresponding Author: Mohamad Faris Mohamad Fathil
Corresponding Author’s Email: mohamadfaris@unimap.edu.my

Download: PDF

Filed Under: Publications Tagged With: Biosensors, Chemical modification, II-VI semiconductors, Lithography, Monoclonal antibodies, Silicon on insulator technology, Substrates, Thin films, Zinc oxide

Visit from Prof. Dr. Saleem

July 19, 2018 By Editor

On July 16, 2018, INEE has received visit from Prof. Dr. Saleem, Universiti Kebangsaan Malaysia. During this visit, he was taken to the INEE laboratory and held a brief discussion with INEE’s director, Assoc. Prof. Dr. Ruslinda and some other research fellow.

prof saleem ukm

prof saleem ukm

prof saleem ukm

Filed Under: News Tagged With: prof saleem, visitor

Eid al-Fitr 1439 INEE Celebration

July 19, 2018 By Editor

On July 13, 2018, INEE held an Eid al-Fitr celebration which was also attended by TNC PNI Prof. Dr. Uda Hashim.

inee eid al-fitr

inee eid al-fitr

inee eid al-fitr

inee eid al-fitr

Filed Under: Events Tagged With: eid al-fitr

NEWS @ INEE

  • NanoRoadshow Biotech Exploration – STI 100 Scientists: 100 Schools: 100 Days MOSTI
  • Visit to the Faculty of Science and Trace Analysis and Biosensor COE, Prince of Songkla University
  • Visit and Collaborative Discussion Between INEE, Walailak University, Thailand, and Maejo University Chiang Mai, Thailand
  • Visit by Malaysian Bioeconomy Development Corporation (Bioeconomy Corporation)
  • Staff Retirement Appreciation Ceremony

EVENTS & ACTIVITIES

  • INEE Nano Roadshow – Series 4
  • NanoBiosensor Workshop 2024
  • Invitation To Nanobiosensor Workshop 2024
  • NANO ROADSHOW @ PSNCWU
  • STEM With Community at FESTKON UniMAP 2023
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Institute of Nano Electronic Engineering, Universiti Malaysia Perlis
Lot 106, 108 & 110, Blok A, Taman Pertiwi Indah,
Jalan Kangar-Alor Setar, Seriab 01000 Kangar, Perlis, Malaysia
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